• 
  Oliver Stone

  regizor

• 
  Oliver Stone

  scenarist

• 
  Colin Farrell

  Alexander
• 
  Anthony Hopkins

  Ptolomeu
• 
  Angelina Jolie

  Olympias
• 
  Jared Leto

  Hephaestion
• 
  Rosario Dawson

  Roxanne
• 
  Jonathan Rhys Meyers

  Cassander

• 
  Val Kilmer

  Filip
• 
  Christopher Plummer

  Aristotel
• 
  Elliot Cowan

  Ptolemy
• 
  Oliver Stone
• 
  Joseph Morgan

  Philotas
• 
  Michael Dixon

  Campfire Soldier
• 
  David Leon

  Hermolaous

• 
  Stephane Ferrara

  Bactrian Commander
• 
  Nick Dunning

  Attalus
• 
  Neil Jackson

  Perdiccas
• 
  Charlie Hollway

  băiat
• 
  Annelise Hesme

  Stateira
• 
  Benjamín Benítez

  Amato
• 
  Rab Affleck

  Attalus' Henchman
• 
  Peter Rnic

  Greek Nobleman
• 
  Connor Paolo

  Young Alexander
• 
  John Kavanagh

  Parmenion
• 
  Féodor Atkine

  Roxane's Father
• 
  Rory McCann

  Crateros
• 
  Raz Degan

  Darius III
• 
  Brian McGrath

  Doctor
• 
  Jaran Ngamdee

  Indian Prince
• 
  Bin Bunluerit

  Indian King
• 
  Gary Stretch

  Cleitus
• 
  Erol Sander

  Persian Prince
• 
  Toby Kebbell

  Pausanius
• 
  Brian Blessed

  Wrestling Trainer
• 
  Mick Lally

  Horse Seller
• 
  Tim Pigott-Smith

  Omen Reader
• 
  Fiona O'Shaughnessy

  Nurse
• 
  David Bedella

  Scribe
• 
  Patrick Carroll

  Young Hephaistion
• 
  Morgan Christopher Ferris

  Young Cassander
• 
  Aleczander Gordon

  Young Perdiccas
• 
  Jessie Kamm

  Child Alexander
• 
  Peter Williamson

  Young Nearchus
• 
  Robert Earley

  Young Ptolemy

• 
  Oliver Stone

  producător
• 
  Vangelis

  coloană sonoră