• 
  Keishi Ohtomo

  regizor

• 
  Nobuhiro Watsuki

  scenarist
• 
  Kiyomi Fujii

  scenarist

• 
  Teruyuki Kagawa

  Kanryuu Takeda
• 
  Yosuke Eguchi

  Saito Hajime
• 
  Yû Aoi

  Megumi Takani
• 
  Emi Takei

  Kaoru Kamiya
• 
  Koji Kikkawa

  Jine Udo

• 
  Munetaka Aoki

  Sanosuke Sagara
• 
  Takeru Sato

  Kenshin Himura
• 
  Taketo Tanaka

  Yahiko Myojin
• 
  Eric Vale

  Sanosuke Sagara
• 
  John Swasey

  Jin'e Udo
• 
  Kent Williams

  Aritomo Yamagata (voice)
• 
  Gou Ayano

  Gein (Kanryu's henchman)

• 
  J. Michael Tatum

  Kanryu Takeda
• 
  Josh Grelle

  Gein (voice)
• 
  Trina Nishimura

  Megumi Takani
• 
  Alexis Tipton

  Kaoru Kamiya
• 
  Micah Solusod

  Kenshin Himura

• 
  Shinz

  producător
• 
  William Ireton

  producător executiv