• 
  Ava DuVernay

  regizor

• 
  Jennifer Lee

  scenarist
• 
  Madeleine L'Engle

  scenarist

• 
  Chris Pine

  dr. Alex Murry
• 
  Reese Witherspoon

  dna. Whatsit
• 
  Gugu Mbatha-Raw

  dna. Murry
• 
  Zach Galifianakis
• 
  Michael Peña

  Red

• 
  Oprah Winfrey

  dna. Which
• 
  Bellamy Young
• 
  Rowan Blanchard
• 
  Mindy Kaling

  dna. Who
• 
  André Holland

  Jenkins
• 
  Levi Miller

  Calvin
• 
  Storm Reid

  Meg

• 
  Daniel MacPherson

  tatăl lui Calvin
• 
  Will McCormack
• 
  Jordan Mazarati
• 
  Alexia Rae Castillo
• 
  Deric McCabe

  Charles Wallace
• 
  Akemi Look
• 
  Punnavith Koy
• 
  Ke'Andra Samone
• 
  Sheila M. Lockhart
• 
  Conrad Roberts
• 
  Will Greenburg
• 
  Daniel Lawson Jr.
• 
  Jesse Jacobs
• 
  Kevyn Bashore
• 
  Jasmine Dampiér
• 
  Eric Bell Jr.
• 
  Ce'Ara Riley Evans
• 
  Analise Hoveyda
• 
  Ceasar Romero Evans Jr.
• 
  Kimberlee Oren

• 
  Adam Borba

  producător
• 
  Gianna Isabella

  producător
• 
  James Whitaker

  producător
• 
  Catherine Hand

  producător
• 
  Tobias A. Schliessler

  imagine
• 
  Paco Delgado

  costume
• 
  Spencer Averick

  montaj
• 
  Ramin Djawadi

  coloană sonoră
• 
  Madeleine L'Engle

  după un roman de
• 
  Naomi Shohan

  design de producţie
• 
  Elizabeth Keenan

  decoruri
• 
  Claire Schwartz

  decoruri