• 
  Chloe Bennet

  Daisy Johnson / Quake
• 
  Stan Lee
• 
  Yancey Arias

  Colonel Victor Ramon
• 
  Hiroo Minami

   Henchman #2 (3 episodes, 2016)
• 
  Natalia Cordova-Buckley

  Slingshot
• 
  Matt Berberi

   Henchman #1 (2 episodes, 2016)
• 
  Dale Pavinski

   Alpha Dog (2 episodes, 2016)
• 
  Ming-Na Wen

  2 episodes, 2016

• 
  Clark Gregg

  Phil Coulson
• 
  Iain De Caestecker

  Leo Fitz
• 
  Jason O'Mara

  Jeffrey Mace
• 
  Elizabeth Henstridge

  Jemma Simmons
• 
  Deren LeRoy

  Agent Cecilio
• 
  Marcus Jordan

  Quinjet Pilot
• 
  Henry Simmons

  Alphonso 'Mack' Mackenzie

• 
  Craig Baxley Jr.

  Watchdog #1
• 
  Mario Perez

  Henchman #1
• 
  Alexander Wraith

  Agent Anderson
• 
  Marcus Jordan

  Quinjet Pilot