• 
  Doug Atchison

  regizor

• 
  Doug Atchison

  scenarist

• 
  Keke Palmer

  Akeelah
• 
  Angela Bassett

  Tanya Anderson
• 
  Laurence Fishburne

  Dr. Larabee
• 
  Curtis Armstrong

  Dl. Welch
• 
  Sidney Ganis

  Regional Pronouncer
• 
  Ashlynn Rose

  Additional Voice

• 
  Wolfgang Bodison

  Akeelah's Father
• 
  Brittany Curran

  District Speller #1
• 
  Eddie Steeples

  Derrick-T
• 
  Fay Hauser

  Woman on TV
• 
  Todd Wagner

  Regional Bee Assistant Judge
• 
  Bonita Friedericy

  Volunteer
• 
  Lee Garlington

  Regional Judge

• 
  D.T. Carney
• 
  Tzi Ma

  Mr. Chiu
• 
  Justin Rodgers Hall

  Parent
• 
  Eric Fallecker

  Student
• 
  Lee Thompson Young

  Devon
• 
  Erica Hubbard

  Kiana
• 
  Jeris Poindexter

  Steve
• 
  Sean Michael

  Dylan
• 
  Sara Niemietz

  Polly
• 
  J.R. Villarreal

  Javier
• 
  Julito McCullum

  Terrence
• 
  Dalia Phillips

  Ms. Cross
• 
  Sahara Garey

  Georgia