• 
  Tim Blake Nelson

  regizor

• 
  Tim Blake Nelson

  scenarist

• 
  Kristen Stewart

  Sophie
• 
  Derrick Baskin

  Medical Examiner
• 
  Jacqueline Baum

  Allie
• 
  Glenn Close

  Marcia
• 
  Sam Waterston

  Prof. Walter Zarrow
• 
  David Aaron Baker

  Devlin

• 
  Yul Vazquez

  Dr. Edward Barnes
• 
  Hannah Marks

  Ella Zarrow
• 
  Mickey Sumner

  Nicole
• 
  Katie Chang

  Amy
• 
  J. Bernard Calloway

  Cedar Lemons
• 
  Philip Ettinger

  Roger
• 
  Ivan Goris

  Ignacio

• 
  Ana Marie Calise

  Student
• 
  Scott Cohen

  Dr. Laffer
• 
  K. Todd Freeman

  Joe
• 
  Jessica Hecht

  Jill
• 
  Tim Blake Nelson

  Adam Zarrow
• 
  Natasha Gregson Wagner

  Marta
• 
  Michael Kenneth Williams

  (as Michael K. Williams)
• 
  Korey Jackson

  Actor
• 
  Erica Cho

  Teacher
• 
  Rob Morgan

  Parnell
• 
  Julia Morrison

  Shani
• 
  G. Michelle Robinson

  Gracie
• 
  Annie Parisse

  Rachel
• 
  Ekaterina Samsonov

  Angie
• 
  Corey Stoll

  Sam
• 
  Rob Morgan

  Parnell
• 
  Lisa Benavides

  Dr. Pratt
• 
  Denise Burse

  West Indian Nurse
• 
  Marcus Callender

  Medical Assistant
• 
  Gretchen Mol

  Sarah
• 
  Gloria Reuben

  Meredith
• 
  Kaipo Schwab

  Tenant
• 
  Ekaterina Samsonov

  Angie

• 
  Tim Blake Nelson

  producător
• 
  Dennis Mykytyn

  producător
• 
  Christina Voros

  imagine
• 
  Annie Simon

  costume
• 
  Mako Kamitsuna

  montaj
• 
  Jeff Danna

  coloană sonoră
• 
  Dina Goldman

  design de producţie
• 
  Nora Mendis

  decoruri
• 
  Katrina Whalen

  decoruri