• 
  Laura Prepon

  Chelsea Newman
• 
  Natasha Leggero

  Nikki Natoli
• 
  Austin Butler

  Luke
• 
  Lenny Clarke

  Melvin Newman
• 
  Mark Povinelli

  Todd
• 
  Chelsea Handler

   Sloane (7 episodes, 2012)
• 
  Jake McDorman

  Rick Miller
• 
  Lauren Lapkus

  Dee Dee

• 
  Ali Wong

  Olivia
• 
  Michaela Rose Haas

  8-Year-Old Chelsea
• 
  Bennie the Cat

  Assface
• 
  P.J. Byrne

  Elliot
• 
  Estelle Harris

  Tess
• 
  Nat Faxon

  Tim Kornick
• 
  Andrew Daly

  Marty Mills

• 
  Ryan Stiles

  Jerry
• 
  Michael Cassidy

  Jonathan
• 
  Gilles Marini

  Robert
• 
  Mark Valley

  Chris