• 
  Robert De Niro

  Bruce Pearson
• 
  Michael Moriarty

  Henry 'Author' Wiggen
• 
  Danny Aiello

  Horse
• 
  Selma Diamond

  Tootsie, Hotel switchboard operator
• 
  Tom Signorelli

  Goose Williams
• 
  Vincent Gardenia

  Dutch Schnell
• 
  Ann Wedgeworth

  Katie
• 
  Patrick McVey

  Bruce's Father

• 
  Frederic C. Weiler

  Fotograf
• 
  Hector Elias

  Dego
• 
  Jack Hollander

  Tegwar Player
• 
  Jean David

  Dutch's Wife
• 
  Barbara Babcock

  Team Owner
• 
  Danny Burks

  Perry
• 
  Marshall Efron

  Bradley

• 
  Phil Foster

  Joe Jaros
• 
  Andy Jarrell

  Ugly
• 
  Tom Ligon

  Piney Woods
• 
  Heather MacRae

  Holly Wiggen
• 
  Maurice Rosenfield

  Team Owner