• 
  Makoto Kamiya

  regizor

• 
  Matthew Mercer

  Leon S. Kennedy
• 
  Dave Wittenberg

  Buddy / Alexander 'Sasha' Kozachenko
• 
  Wendee Lee

  Svetlana Belikova
• 
  Carolyn Lawrence

  Ashley Graham
• 
  Courtenay Taylor

  Ada Wong
• 
  David Earnest

  Secretary
• 
  Michael McConnohie

  Tyrant

• 
  Patrick Harlan

  Ark Thompson
• 
  Patrick Seitz

  Scarecrow
• 
  Robin Sachs

  Ataman / Ivan Judanovich
• 
  Salli Saffioti

  Ingrid Hunnigan
• 
  Val Tasso

  JD
• 
  Dave Earnest

  Secretary (voice) (as David Earnest)

• 
  Hiroyuki Kobayashi

  producător