• 
  David S. Goyer

  regizor

• 
  David S. Goyer

  scenarist

• 
  Wesley Snipes

  Blade
• 
  Jessica Biel

  Abigail Whistler
• 
  Ryan Reynolds

  Hannibal King
• 
  Kris Kristofferson

  Abraham Whistler
• 
  Dominic Purcell

  Dracula (Drake)
• 
  Parker Posey

  Danica Talos

• 
  Scott Heindl

  Gedge
• 
  John Ashker

  Campbell
• 
  James Remar

  Ray Cumberland
• 
  Chris Gorak

  Doctor
• 
  Natasha Lyonne

  Sommerfield
• 
  Erica Cerra

  Goth Vixen Wannabe
• 
  Christopher Heyerdahl

  Caulder

• 
  Eric Bogosian

  Bentley Tittle
• 
  Gabriel Beristain

  One-Eyed Newspaper Vendor
• 
  Cascy Beddow

  Flick
• 
  Kwesi Ameyaw

  Agent
• 
  Ron Selmour

  Dex
• 
  Clay Cullen

  Stone
• 
  Darryl Scheelar

  Doctor
• 
  Garvin Cross

  Hoop
• 
  Kimani Ray Smith

  Doh
• 
  Darren McGuire

  Emond
• 
  Brian Steele

  Drake Creature
• 
  Alejandro Rae

  Goth Guy Wannabe
• 
  John Michael Higgins

  Dr. Edgar Vance
• 
  Kett Turton

  Dingo
• 
  Callum Rennie

  Asher Talos
• 
  Paul Levesque

  Jarko Grimwood
• 
  Patton Oswalt

  Hedges
• 
  Jordan Hoffart

  Squid
• 
  Mark Berry

  Chief Martin Vreede
• 
  Michael Rawlins

  Wilson Hale
• 
  Françoise Yip

  Virago
• 
  Paul Anthony

  Wolfe