• 
  Jan Kounen

  regizor

• 
  Vincent Cassel

  Mike Blueberry
• 
  Michael Madsen

  Wallace Sebastian Blount
• 
  Juliette Lewis

  Maria Sullivan
• 
  Temuera Morrison

  Runi
• 
  Colm Meaney

  Jimmy McLure
• 
  Djimon Hounsou

  Woodhead
• 
  Tchéky Karyo

  Unchiul

• 
  Ernest Borgnine

  Rolling Star
• 
  Nichole Hiltz

  Lola
• 
  Jean Giraud
• 
  Dominique Bettenfeld

  Toothless Man
• 
  Pascal Demolon

  Dentist
• 
  Chattoune

  Leader of the Vertue Ligue
• 
  Geoffrey Lewis

  Greg Sullivan

• 
  Tetsuo Nagata

  Chiricahua Man
• 
  Jan Kounen

  Billy
• 
  Hugh O'Conor

  Young Mike Blueberry
• 
  Eddie Izzard

  Prosit
• 
  François Levantal

  Pete the Barman
• 
  Juan Manuel Bernal

  Jeremy
• 
  Vahina Giocante

  Madeleine
• 
  Val Avery

  Judecător
• 
  Kateri Walker

  Kateri
• 
  Guillermo Arévalo

  Kheetseen (as Kestenbetsa)