• 
  Jed Mercurio

  regizor

• 
  Jed Mercurio

  scenarist

• 
  Max Beesley

  Dr. Rob Lake
• 
  Preeya Kalidas

  Dr. Maya Dutta (7 episodes, 2004-2005)
• 
  Patrick Baladi

  Dr. Roger Hurley
• 
  Susan Lynch

  Dr. Maria Orton
• 
  Sarah-Jane Potts

  Ruth Duncan (1 episode, 2005)
• 
  Nicholas Palliser

  Paul Tennant (4 episodes, 2004-2005)

• 
  Hannah Yelland

  Laura Johnson (1 episode, 2005)
• 
  Alison Burrows

  Sophie Haddon (1 episode, 2004)
• 
  Angela Murray

  Melanie Groves (1 episode, 2005)
• 
  Tiggy Allen

  Siobhan Riley (1 episode, 2005)
• 
  Ingeborga Dapkunaite

  Katya Bredova (5 episodes, 2004)
• 
  Joe Tucker

  Rich (1 episode, 2006)
• 
  Neve McIntosh

  Sister Donna Rix (16 episodes, 2004-2006)

• 
  Oliver Milburn

  James Moore (1 episode, 2005)
• 
  Susan Cookson

  Yvonne Matthews (6 episodes, 2004)
• 
  Paul Sharma

  Darpak Gill (1 episode, 2004)
• 
  Steve Furst

  Brian Richards (1 episode, 2005)
• 
  Jayne Ashbourne

  Anne-Marie (4 episodes, 2004)
• 
  Katy Cavanagh

  Harriet Hurley (2 episodes, 2005)
• 
  Saskia Reeves

  Mary Dodd (1 episode, 2006)
• 
  Keith Allen

  Mr. Tony Whitman (16 episodes, 2004-2006)
• 
  Tamzin Malleson

  Dr. Polly Grey (16 episodes, 2004-2006)
• 
  Paul Oldham

  Burnt Woman's Boyfriend (1 episode, 2004)
• 
  Ace Bhatti

  Raj (1 episode, 2004)
• 
  Sophie Lombard

  Dr. Consuela Gonzalez Rivera  (2 episodes, 2004)
• 
  Karen Bryson

   Hazel Melrose (14 episodes, 2004-2005)
• 
  Liz Hume Dawson

   Dottie Sands (12 episodes, 2004-2005)
• 
  Simon Lowe

  Tim Sibley
• 
  Hattie Morahan

   Beth Lucas Hall / ... (7 episodes, 2005)
• 
  Vicky Hall

   Chrissy Farrell (9 episodes, 2005-2006)
• 
  Rhashan Stone

   Tom Gorman (9 episodes, 2004-2005)