• 
  Andrew V. McLaglen

  regizor

• 
  Barney Slater

  scenarist

• 
  John Wayne

  U.S. Marshal J.D. Cahill
• 
  George Kennedy

  Abe Fraser
• 
  Gary Grimes

  Danny Cahill
• 
  Walter Barnes

  Sheriff Grady, Valentine Texas
• 
  Murray MacLeod

  Deputy Sheriff Gordine
• 
  Neville Brand

  Lightfoot, Half-breed Comanche tracker

• 
  Marie Windsor

  Mrs. Hetty Green
• 
  Paul Fix

  Old Man, Outlaw
• 
  Royal Dano

  MacDonald, Hermit who sells Cahill the mule
• 
  Jackie Coogan

  Charlie Smith, Town Drunk
• 
  Chuck Roberson

  Leader of Bunch
• 
  Morgan Paull

  Struther, Fraser Gang/Cahill's Ward
• 
  Harry Carey Jr.

  Hank, Jailer at Jefferson Davis County Jail

• 
  Denver Pyle

  Denver, Danny & Billy Joe's caretaker
• 
  Pepper Martin

  Hard Case
• 
  Hank Worden

  Albert, Valentine Stationmaster
• 
  Rayford Barnes

  Pee Wee Simser
• 
  Dan Kemp

  Joe Meehan
• 
  Clay O'Brien

  Billy Joe
• 
  Morgan Paull

  Struther
• 
  Dan Vadis

  Brownie
• 
  Scott Walker

  Ben Tildy