• 
  John Ford

  regizor

• 
  James Stewart

  Wyatt Earp
• 
  Edward G. Robinson

  the Secretary of the Interior
• 
  Carroll Baker

  Deborah Wright
• 
  James Flavin

  Ft. Robinson sergeant of the guard
• 
  Harry Hickox

  Barman
• 
  Sal Mineo

  Red Shirt
• 
  Carleton Young

  Aide to Carl Schurz

• 
  Harry Holcombe

  Senator
• 
  Bing Russell

  Braden's Telegraph Operator
• 
  Richard Widmark

  Capt. Thomas Archer
• 
  Ricardo Montalban

  Little Wolf
• 
  John Carradine

  Jeff Blair
• 
  Danny Borzage

  Trooper
• 
  James O'Hara

  Trooper

• 
  Carmen D'Antonio

  Pawnee Woman
• 
  Judson Pratt

  Mayor Dog Kelly
• 
  Charles Seel

  Newspaper publisher
• 
  Karl Malden

  Capt. Wessels
• 
  William Henry

  Infantry captain
• 
  Walter Baldwin

  Jeremy Wright (Deborah's uncle)
• 
  Mike Mazurki

  Sr. First Sergeant
• 
  Chuck Roberson

  Jessie (Texas trail boss)
• 
  Ben Johnson

  Trooper Plumtree
• 
  Jeannie Epper

  Entertainer
• 
  Chuck Hayward

  Trooper
• 
  Harry Carey Jr.

  Trooper Smith
• 
  Mae Marsh

  Woman
• 
  Denver Pyle

  Sen. Henry
• 
  Ken Curtis (I)

  Joe
• 
  George O'Brien

  Major Braden
• 
  Victor Jory

  Tall Tree
• 
  Patrick Wayne

  Second Lieut. Scott
• 
  Dolores del Rio

  Spanish Woman
• 
  Elizabeth Allen

  Miss Plantagenet
• 
  Arthur Kennedy

  Doc Holliday
• 
  Sean McClory

  Dr. O'Carberry
• 
  Gilbert Roland

  Dull Knife