• 
  Jamie Marchi

   Junko Enoshima (4 episodes, 2013)
• 
  Kazuya Nakai

   Mondo Oowada (5 episodes, 2013)
• 
  Akira Ishida

   Byakuya Togami (13 episodes, 2013)
• 
  Megumi Ogata

   Makoto Naegi (13 episodes, 2013)
• 
  Nobuyo Ohyama

   Monokuma (13 episodes, 2013)
• 
  Hekiru Shiina

   Celestia Ludenberg (7 episodes, 2013)
• 
  Kappei Yamaguchi

   Hifumi Yamada (7 episodes, 2013)
• 
  Kosuke Toriumi

   Kiyotaka Ishimaru (6 episodes, 2013)

• 
  Kouki Miyata

   Chihiro Fujisaki / ... (6 episodes, 2013)
• 
  Miyuki Sawashiro

   Toko Fukawa (13 episodes, 2013)
• 
  Kujira

   Sakura Ôgami (9 episodes, 2013)
• 
  Chiwa Saito

   Aoi Asahina (13 episodes, 2013)
• 
  Yôko Hikasa

   Kyôko Kirigiri (13 episodes, 2013)
• 
  Masaya Matsukaze

   Yasuhiro Hagakure (13 episodes, 2013)
• 
  Lindsay Seidel

   Celestia Ludenburg (7 episodes, 2013)

• 
  Bryce Papenbrook

   Naegi (13 episodes, 2013)
• 
  Christopher Sabat

   Owada (7 episodes, 2013)
• 
  Kara Edwards

   Fujisaki / ... (9 episodes, 2013)
• 
  Christopher Bevins

   Hagakure (13 episodes, 2013)
• 
  Rachel Robinson

   Ogami / ... (9 episodes, 2013)
• 
  Greg Ayres

  Monokuma
• 
  Caitlin Glass

   Kirigiri (13 episodes, 2013)
• 
  Josh Grelle

   Togami (13 episodes, 2013)
• 
  Carli Mosier

   Fukawa (13 episodes, 2013)
• 
  Austin Tindle

   Ishimaru (6 episodes, 2013)
• 
  Tyson Rinehart

   Yamada (7 episodes, 2013)
• 
  Felecia Angelle

   Asahina (13 episodes, 2013)
• 
  Massaya Matsuzake Ono

  Yasuhiro Hagakure