• 
  James Franco

  Johnny
• 
  Lynn Cohen

  Edith Jane
• 
  Iliza Shlesinger

  Shelly
• 
  Brooke Lyons

  Bloody Mary
• 
  Danny DeVito

  Giuseppe Monamocce
• 
  Zachary Levi

  Abraham Lincoln
• 
  Cat Deeley

   Camomile / ... (6 episodes, 2014)
• 
  Tyler Labine

   Kevin Pacalioglu / ... (10 episodes, 2014)

• 
  Brandon T. Jackson

   Roofie (10 episodes, 2014)
• 
  Lucy DeVito

   Sue (11 episodes, 2014-2015)
• 
  Meryl Hathaway

   Millie (5 episodes, 2015)
• 
  Kal Penn

   Clyde (13 episodes, 2016)
• 
  Paul Fitzgerald

  Detective Crosby
• 
  Matthew Porretta

  Crosby
• 
  Brad Williams

  Tyson

• 
  Todd Alan Crain

  Wesley Chilcott
• 
  Modi

  Menachem Mendel
• 
  Jeff Solomon

  Bartender
• 
  Kurt Braunohler

  Danny 'Poker' Pokertini
• 
  Brett Konner

  Blob
• 
  Michael S. Chandler

  Construction Foreman
• 
  Jeremy Shinder

  Young Pac
• 
  Trey Gerrald

  Reality Producer
• 
  Lauren Adams

  Carol
• 
  Michael Kostroff

  Barrold Weinbergerstein