• 
  John Malkovich

  dr. Felton
• 
  Romola Garai

  Caitlin Thomas
• 
  Rhys Ifans

  Dylan Thomas
• 
  Noel Burton

  Jeremy
• 
  Ellen David

  Dorothy
• 
  Tony Hale

  Brinnan
• 
  Jonathan Higgins

  Julian (Publisher #2)
• 
  Arthur Holden

  Dean

• 
  Zosia Mamet

  Penny
• 
  Rodrigo Santoro

  Carlos
• 
  Guy Sprung

  Felix
• 
  Mike Paterson

  Teddy
• 
  Shawn Zimmerman

  Caitlin's Lover
• 
  Jeremy Ferdman

  Michael
• 
  Andrew Shaver

  Reggie - Publisher #1

• 
  Philip Ettinger

  Alexi
• 
  Elizabeth Neale

  Medical student
• 
  Nina Lauren

  Utility Stand-In
• 
  Michael Riendeau

  Colm Thomas
• 
  Adam Alberts

  Student