• 
  Andrzej Bartkowiak

  regizor

• 
  Karl Urban

  John Grimm
• 
  Dwayne Johnson

  Sarge
• 
  Deobia Oparei

  Destroyer
• 
  Rosamund Pike

  Samantha Grimm
• 
  Razaaq Adoti

  Duke
• 
  Richard Brake

  Corporal Dean Portman
• 
  Dexter Fletcher

  Pinky

• 
  Doug Jones

  Dr. Carmack Imp/Sewer Imp/FPS Imp
• 
  Brian Steele

  Hell Knight / Curtis Stahl
• 
  Al Weaver

  The Kid
• 
  Ben Daniels

  Goat
• 
  Rana Morrison

  Female evacuee
• 
  Barbara Nedeljakova

  Girl at bar
• 
  Sara Houghton

  Dr. Jenna Willits

• 
  Daniel York

  Lt. Huengs
• 
  Robert Russell

  Dr. Carmack
• 
  Yao Chin

  Mac
• 
  Ian Hughes

  Sanford Crosby