• 
  Rouben Mamoulian

  regizor

• 
  Samuel Hoffenstein

  scenarist
• 
  Percy Heath

  scenarist

• 
  Fredric March

  Dr. Henry L. Jekyll / Mr. Hyde
• 
  Holmes Herbert

  Dr. Lanyon
• 
  Rose Hobart

  Muriel Carew
• 
  Halliwell Hobbes

  Brig. Gen. Danvers Carew
• 
  Miriam Hopkins

  Ivy Pearson

• 
  Douglas Walton

  Blond Student
• 
  Edgar Norton

  Poole
• 
  Arnold Lucy

  Utterson
• 
  Eric Wilton

  Briggs - Lanyon's Butler
• 
  Tempe Pigott

  Mrs. Hawkins

• 
  Rouben Mamoulian

  producător
• 
  Hans Dreier

  scenografie

• 
  Karl Struss

  imagine
• 
  William Shea

  montaj
• 
  Adolph Zukor

  producător executiv
• 
  Robert Louis Stevenson

  după un roman de