• 
  Liam Neeson
• 
  Daniella Pineda
• 
  Bill Bellamy

   Officer Cosgrove
• 
  Geoffrey Arend

   Patient #086
• 
  Dave Coulier

   Himself
• 
  Jon Gries

   Dr. Roberts
• 
  Clint Howard

   Carl Kwartz
• 
  Cleo King

   General Jim

• 
  Tembi Locke

   Gutierrez
• 
  Stephen Merchant

   TERRY
• 
  Josh Meyers

   Kyle T
• 
  Mary Lynn Rajskub

   Patient #046
• 
  June Squibb

   Patient #054
• 
  Stephnie Weir

   Diane Thrippleton
• 
  Mark Proksch

   Randy Blink

• 
  Stephanie Allynne

   Joey
• 
  Breeda Wool

   Mother
• 
  Dan Gill

   Patient #103
• 
  Nicholas Rutherford

   Patient #088 (6 episodes)
• 
  Ahmed Bharoocha

   Ahmed (6 episodes)
• 
  Megan Ferguson

   Bea (6 episodes, 2017)
• 
  Sunita Mani

  Margot Daly
• 
  Kahlea Baldwin

  Helen Balbis
• 
  Jon Black

  Sign Spinner
• 
  Maria Bamford

  Norf Norf
• 
  Mo Collins

  Patient 30
• 
  Jo Farkas

  Louise
• 
  Bobby Lee

  Tricky Ricky
• 
  Jesse Merlin

  Barreleye Fish
• 
  Rupert Friend

  Patient 62
• 
  Jimmi Simpson

  Patient 21