• 
  Aidan Quinn

  Captain Thomas Gregson
• 
  Edoardo Ballerini

  Agent Lukas Muller
• 
  Reed Diamond

  Joel Fitzgerald
• 
  Joel Marsh Garland

  Manager
• 
  John Jellison

  Old Man
• 
  John Noble

  Mr. Morland Holmes
• 
  Jonathan Sale

  Another ESU Officer
• 
  John Shea

  Bill Wellstone

• 
  Michael Esper

  Donald Pruitt
• 
  Andrew Breving

  Executive
• 
  Celia Keenan-Bolger

  Amber Bova
• 
  Will Cobbs

  ESU Officer #1
• 
  Jon Michael Hill

  Detective Marcus Bell
• 
  Jonny Lee Miller

  Sherlock Holmes
• 
  Lucy Liu

  Dr. Joan Watson