• 
  Aidan Quinn

  Captain Thomas Gregson
• 
  Christina Cox

  Christa Pullman
• 
  Lauren Luna Vélez

  Zoe Mercado (as Luna Velez)
• 
  Samantha Quan

  Lin Wen
• 
  Quentin Mare

  Ephraim Hill
• 
  Tijuana Ricks

  Teri
• 
  Zanny Laird

  Marissa Kagan
• 
  Jason Dirden

  Keith Elliot

• 
  Evan Hall

  Louis Bowman
• 
  Jon Michael Hill

  Detective Marcus Bell
• 
  Lauren Culpepper

  Skyden
• 
  Margo Seibert

  Amanda Neal
• 
  Victoria Janicki

  Phoebe Elliot
• 
  Jonny Lee Miller

  Sherlock Holmes
• 
  Lucy Liu

  Dr. Joan Watson