• 
  John C. Reilly

  John
• 
  Gregg Turkington

  The Comedian
• 
  Tye Sheridan

  Eddie
• 
  Kalia Prescott

  Maria
• 
  Dean Stockwell

  Frank
• 
  Tonantzin Carmelo

  Teresa
• 
  Annabella Lwin

  Rachel
• 
  David Yow

  Party Host

• 
  Dustin Guy Defa

  Ruben
• 
  Amy Seimetz

  Rene
• 
  Tim Heidecker

  The Celebrity
• 
  Lotte Verbeek

  The Chromotherapist
• 
  Mariann Gavelo

  Sitcom Maria
• 
  Waymond Lee

  Prisoner
• 
  Ashley Atwood

  Pregnant Woman

• 
  Brenna Rhea

  Poolside Girl
• 
  William Echeverri

  Prisoner
• 
  Becktoria

  Bikini Girl
• 
  Carlos Simental Jr.

  Prisoner
• 
  Juan Cueto

  John's Father-in-Law
• 
  Mike Hickey

  The Heckler
• 
  Lawrence Michael Levine

  Heckler Voice
• 
  Sergio Estrada

  Alejandro
• 
  Craig Holland

  Oil Field Tour Guide
• 
  Fabian Euresti

  Orange Grove Worker
• 
  Susan Cernas

  Alejandro's Daughter Maria
• 
  Kevin Guthrie

  Ghost Town Tour Guide
• 
  Juventino Martin

  Gael
• 
  Michael Cera

  Tommy