• 
  James Whale

  regizor

• 
  Peggy Webling

  scenarist

• 
  Colin Clive

  Dr. Henry Frankenstein
• 
  Boris Karloff

  Monstrul
• 
  Mae Clarke

  Elizabeth
• 
  John Boles

  Victor Moritz
• 
  Edward Van Sloan
• 
  Ellinor Vanderveer

  Medical student

• 
  Francis Ford (I)

  Hans
• 
  Cecilia Parker

  Maid
• 
  Lionel Belmore

  Herr Vogel
• 
  Dwight Frye

  Fritz
• 
  Mary Gordon

  Mourner
• 
  Mae Bruce

  Screaming Maid
• 
  Ted Billings

  Villager

• 
  Marilyn Harris

  Little Maria
• 
  Frederick Kerr

  Baron Frankenstein