• 
  Jack Smight

  regizor

• 
  Jane Seymour

  Agatha / Prima
• 
  James Mason

  Dr. John Polidori
• 
  Clarissa Kaye-Mason

  Lady Fanschawe
• 
  Leonard Whiting

  Dr. Victor Frankenstein
• 
  Ralph Richardson

  Mr. Lacey
• 
  David McCallum

  Dr. Henry Clerval
• 
  John Gielgud

  Chief Constable (Police)

• 
  Agnes Moorehead

  Mrs. Blair
• 
  Norman Rossington

  Seaman
• 
  Michael Wilding

  Sir Richard Fanshawe
• 
  Michael Sarrazin

  The Creature
• 
  Peter Sallis
• 
  Julian Barnes

  tânăr
• 
  Tom Baker

  Sea Captain

• 
  Margaret Leighton

  Francoise DuVal
• 
  Arnold Diamond

  Passenger in Coach

• 
  Fred Carter

  art director
• 
  Arthur Ibbetson

  imagine
• 
  Gil Melle

  departament sunet
• 
  Wilfred Shingleton

  design de producţie
• 
  Ken Barker (I)

  sound department
• 
  Graham V. Hartstone

  sound department
• 
  Don Sharp

  sound department
• 
  Mary Shelley

  scriitor
• 
  Christopher Isherwood

  scriitor