• 
  James Woods

  Hades (voce)
• 
  Eric Stoltz

  Theseus / The Grim Avenger
• 
  Barbara Barrie

  Alcmene (voce)
• 
  Eric Idle

  Parenthesis
• 
  Wayne Knight

  Orthus
• 
  Carole Shelley

  Lachesis
• 
  Tress MacNeille

  Clotho
• 
  Corey Burton

  Zeus

• 
  Tate Donovan

  Hercules
• 
  Diedrich Bader

  Adonis
• 
  Michael Dorn

  Minotaur
• 
  French Stewart

  Icarus
• 
  Jodi Benson

  Helen of Troy
• 
  Sandra Bernhard

  Cassandra
• 
  Matt Frewer

  Panic

• 
  Bobcat Goldthwait

  Pain
• 
  Brad Garrett

  Orthus
• 
  Bill Fagerbakke

  Cyclops
• 
  Cheryl Freeman

  Mepomene
• 
  Jay Thomas (I)

  Ares
• 
  Kathie Lee Gifford

  Echidna
• 
  Robert Costanzo

  Philoctetes