• 
  John Wayne

  Daniel F. Somers
• 
  Rhonda Fleming

  Dance-hall girl
• 
  Dick Rich

  Card player on train
• 
  Charles Sherlock

  Scared wagon driver
• 
  Hooper Atchley

  Witherspoon's Assistant
• 
  Lane Chandler

  Card player on train
• 
  Irving Bacon

  Ben (telegraph operator)
• 
  Sidney Blackmer

  Teddy Roosevelt

• 
  William H. Wright

  Doctor
• 
  Robert Warwick

  Chief Big Tree
• 
  Albert Dekker

  Jim 'Hunk' Gardner (president, Gardner Oil Co.)
• 
  Martha Scott

  Catherine Elizabeth Allen
• 
  Paul Fix

  Cherokee Kid
• 
  Byron Foulger

  Wilkins
• 
  Stanley Andrews

  Mason (Indian agent)

• 
  LeRoy Mason

  Promoter
• 
  Fred Graham

  Gardner's man
• 
  William Davidson

  Master of Ceremonies
• 
  Wade Crosby

  Corrigan (oiler)
• 
  Curley Dresden

  Second randy train passenger
• 
  George 'Gabby' Hayes

  Despirit Dean (stage driver)
• 
  Al Hill

  Chelner
• 
  Roy Barcroft

  Oil worker on train
• 
  Eddy Chandler

  McCann, Gardner's Oil Man
• 
  Will Wright

  Doctor
• 
  Harry Shannon

  Charlie Witherspoon