• 
  Jack Black

  Po (voce)
• 
  James Hong

  Mr. Ping (voce)
• 
  Eliott Guenoden

  Young Bunny (voce)
• 
  Dustin Hoffman

  Shifu (voce)
• 
  Lucy Liu

  Vipera (voce)
• 
  David Cross

  Crane
• 
  Stephen Kearin

  Master Mongrel
• 
  Randall Duk Kim

  Oogway

• 
  Jayden Lund

  Boar
• 
  Tara Macri

  Young Tigress
• 
  Seth Rogen

  Mantis
• 
  James Sie

  Monkey
• 
  Joseph Izzo

  Palace Goose
• 
  Peter Cilella

  Goat
• 
  Jerry Clarke

  Gorilla

• 
  Kelly Stables

  (voce)