• 
  Beryl Richards

  regizor
• 
  Steve Hughes

  regizor

• 
  Dan Danko

  scenarist

• 
  Flora Spencer-Longhurst

  Lisa
• 
  Jonathan Bailey

  Leonardo
• 
  Akemnji Ndifernyan

  Machiavelli
• 
  James Clyde

  Piero De Medici
• 
  Colin Ryan

  Lorenzo

• 
  James Cunningham

  Verrocchio
• 
  Thembalethu Ntuli

   Cosimo / ... (11 episodes, 2011-2012)
• 
  Alistair McGowan

  13 episodes, 2011
• 
  James Cunningham

  Verrocchio
• 
  Camilla Waldman

  Teresa De Medici
• 
  Bart Fouche

  Placidi
• 
  Chris Olley

  Caporaso

• 
  Graham Hopkins

  The Duke
• 
  Roxane Hayward

  Angelica
• 
  Clayton Boyd

  Rocco De Medici
• 
  Mike Huff

  Valerio
• 
  Anthony Bishop

  Placidi
• 
  John Herbert

  Mazzini
• 
  Adam Neill

  Donnola