• 
  Trea Bertrille

  Follower
• 
  Raul Colon

  Damian Boss Mode
• 
  Tyler Suggs

  Infected
• 
  Jimmy Dempster

  Messiah
• 
  D.J. Rivera

  TC-ALpha (voice)
• 
  Benjamin Bernard

  Chad
• 
  Jared Kent

  Damian
• 
  Audrey Dempster

  Violet, Infected

• 
  Anthony Giovanni Elias

  Infected Ambush 1
• 
  Derek Fernando Leavitt

  Infected Ambush 2
• 
  Jacquelynne Faith

  Roxy
• 
  Zachary Simon

  Patient Zero
• 
  Javier Mendez

  News Anchor 1 (voice)
• 
  Angel Perez

  Infected Ambush 3
• 
  Chase Rangel

  Xander

• 
  David Walterhouse

  Young Boy (voice)
• 
  Cesar Perez-Babilonia

  Infected Ambush 4
• 
  James Hurley

  News Anchor 2 (voice)
• 
  Joshua Wilson

  Infected (voice)
• 
  Henry Grun

  Infected Juggernaut
• 
  Javier Méndez

  News Anchor 1 (voice) (as Javier Mendez)