• 
  James Stewart

  Jason Wilkins
• 
  Sterling Holloway

  Chauncey Ames
• 
  Frank McGlynn Sr.

  Lout
• 
  William Stack

  Uniform Salesman
• 
  Brenda Fowler

  Mrs. Ames
• 
  Beulah Bondi

  Mary Wilkins
• 
  Jules Cowles

  Churchgoer
• 
  Frank Reicher

  Ofiţer

• 
  John Miljan

  Capt. Griggs
• 
  Stanley Fields

  Horse Owner
• 
  Clem Bevans

  Elder Massey
• 
  Guy Kibbee

  George Ames
• 
  Leona Roberts

  Sister Clarke
• 
  John Carradine

  President Abraham Lincoln
• 
  Phillip Terry

  Army Intern

• 
  Charles Coburn

  Dr. Charles Shingle
• 
  Ted Healy
• 
  Robert McWade

  Dr. Lupus Crumm
• 
  Charles Trowbridge

  Doctor attending Capt. Griggs
• 
  Charley Grapewin

  Jim Meeker
• 
  Ward Bond

  Lout Laughing in Church
• 
  Gene Reynolds

  Jason Wilkins as a Child
• 
  Ann Rutherford

  Annie Hawks
• 
  Gene Lockhart

  Quid, the Janitor
• 
  Arthur Aylesworth

  Rufus Inchpin
• 
  Leatrice Joy Gilbert

  Annie Hawks as a Child
• 
  Walter Huston

  Ethan Wilkins