• 
  Dylan Kussman

  Attorney
• 
  Tony Schnur

  Surgeon
• 
  Stephen Colletti

  Chase Adams
• 
  Kate Voegele

  Mia Catalano
• 
  Daphne Zuniga

  Victoria Davis
• 
  Robert Buckley

  Clay Evans
• 
  Sophia Bush

  Brooke Davis
• 
  James Lafferty

  Nathan Scott

• 
  Bethany Joy Lenz

  Haley James Scott (as Bethany Joy Galeotti)
• 
  Austin Nichols

  Julian Baker
• 
  Lee Norris

  Marvin 'Mouth' McFadden
• 
  Jana Kramer

  Alex Dupré
• 
  Shantel VanSanten

  Quinn James
• 
  Jackson Brundage

  Jamie Scott
• 
  Lisa Goldstein

  Millicent 'Millie' Huxtable (as Lisa Goldstein)