• 
  Bob Koherr

  regizor

• 
  Marc Firek

  scenarist

• 
  Jennifer Tilly

  Crystal
• 
  Krista Allen

  Kathy Kelly
• 
  Paula Marshall

  Dr. Regina Barnes
• 
  Christopher Gorham

  Dr. Benjamin Barnes
• 
  Ty Burrell

  Dr. Oliver Barnes
• 
  Annie Wersching

  Conner

• 
  Wendie Malick

  Lois Turner (1 episode, 2005)
• 
  E.J. Callahan

  Curtis (1 episode, 2005)
• 
  Tangie Ambrose

  Bianca (1 episode, 2005)
• 
  Brooks Almy

  Enid (1 episode, 2005)
• 
  Sandra Robinson

  Sophie (1 episode, 2005)
• 
  Kevin Daniels

  Bartender (1 episode, 2006)
• 
  Todd Stashwick

  Frankie (1 episode, 2005)

• 
  Andrea Bogart

  Elizabeth (1 episode, 2006)
• 
  Stockard Channing

  Dr. Lydia Barnes (20 episodes, 2005-2006)
• 
  Jill Latiano

  Wendy (1 episode)
• 
  Jarrod Bailey

  Billy (1 episode, 2005)
• 
  Kevin Makely

  Eric (1 episode, 2005)
• 
  Marion Ross

  Norma (1 episode, 2006)
• 
  Diane Sellers

  Nurse Erin (2 episodes, 2005-2006)
• 
  Carol Ann Susi

  Susy (2 episodes, 2005)
• 
  Mary Anne McGarry

  Cynthia Boyd (1 episode, 2006)
• 
  Adriana DeMeo

  Amy (1 episode, 2005)
• 
  Elena Lyons

  Joanna (1 episode, 2006)
• 
  Valerie Curtin

  Frieda (1 episode, 2006)
• 
  Henry Winkler

  Dr. Stewart Barnes (20 episodes, 2005-2006)
• 
  Doug Budin

  Maitre D' (1 episode, 2006)
• 
  Lisa Banes

  Chef Vivian (1 episode, 2005)
• 
  James Naughton

  Dr. Jack Arbogast (2 episodes, 2006)
• 
  Kimberly Oja

  Liz (1 episode, 2005)
• 
  Barry Bostwick

  Gavin (2 episodes, 2005-2006)
• 
  Jamie Elle Mann

  Tina (1 episode, 2005)
• 
  Jenna Gering

  Gail Henson (1 episode, 2005)
• 
  Stephanie Faracy

  Laura (1 episode, 2005)
• 
  Dorie Barton

  Patty (1 episode, 2005)
• 
  Rebecca Budig

  Dr. Carla Munson (1 episode, 2006)
• 
  Kate Levering

  Jennifer (1 episode, 2005)
• 
  Valerie Mahaffey

  Barb (1 episode, 2005)
• 
  Kristen Miller

  Sharon (1 episode, 2005)
• 
  Marcus Folmar

  Orderly (1 episode, 2005)
• 
  Christopher Stapleton

  Steve (1 episode, 2005)
• 
  Roger Bart

  Lou Pimsky (1 episode, 2005)
• 
  Jennifer O'Dell

  Cynthia (1 episode, 2005)
• 
  Peg Shirley

  Joyce (1 episode, 2005)
• 
  Tyrone Giordano

  Dr. Robert Winslow (1 episode, 2006)
• 
  Terri Hoyos

  Carmen (1 episode, 2006)
• 
  Jordana Spiro

  Bianca  (2 episodes, 2005)
• 
  Constance Zimmer

  Naomi (2 episodes, 2005-2006)
• 
  Kristin Richardson

  Trisha (1 episode, 2006)
• 
  Steven Gilborn

  Irv (1 episode, 2005)
• 
  Kaitlin Olson

  Debbie (1 episode, 2006)
• 
  Nadia Bjorlin

  Alana (1 episode, 2006)