• 
  Rachael Lillis

  Jessie
• 
  Eric Stuart

  James
• 
  Veronica Taylor

  Ash Ketchum
• 
  Ken Gates

   Narrator (4 episodes, 2013)
• 
  Jimmy Zoppi

   James / ... (4 episodes, 2013)
• 
  Lisa Ortiz

   Fletchling (3 episodes, 2013)
• 
  Lori Gardner

   Viola (2 episodes, 2013)
• 
  Michele Knotz

   Jessie (4 episodes, 2013)

• 
  Bella Hudson

   Grace (3 episodes, 2013)
• 
  Jacob Paque

   Professor Sycamore (3 episodes, 2013)
• 
  Rebecca Soler

   Alexa (3 episodes, 2013)
• 
  Alyson Leigh Rosenfeld

   Bonnie / ... (4 episodes, 2013)
• 
  Mike Liscio

   Clemont (4 episodes, 2013)
• 
  Jessica Paquet

   Alexa (3 episodes, 2013)
• 
  Haven Paschall

   Serena (4 episodes, 2013)

• 
  Eileen Stevens

  Fennekin
• 
  Ikue Ootani

  Pikachu
• 
  David Errigo Jr.

   Nihei (2 episodes, 2015)
• 
  Christopher Collet

  638 episodes, 2002-2016
• 
  Megumi Hayashibara

  735 episodes, 1997-2017
• 
  Inuko Inuyama

  689 episodes, 1997-2017
• 
  Unshô Ishizuka

  773 episodes, 1997-2016
• 
  Rica Matsumoto

  Satoshi
• 
  Shinichirô Miki

  813 episodes, 1997-2014
• 
  Kayzie Rogers

  769 episodes, 1997-2016
• 
  Yûji Ueda

  Takeshi
• 
  Sarah Natochenny

  Ash Ketchum
• 
  Addie Blaustein

  Meowth