• 
  Rachael Leigh Cook

  Josie McCoy
• 
  Fred Armisen

  Archie Andrews
• 
  Hugh Davidson

  (voice)
• 
  Ryan Phillippe

  Reggie Mantle
• 
  Seth Green

  (voice)
• 
  Breckin Meyer

  (voice)
• 
  Donald Faison

  (voice)
• 
  Jared Harris

  Mr. Weatherbee

• 
  Jane Lynch

  Miss Grundy
• 
  Katee Sackhoff

  Hilda Spellman
• 
  Amy Sedaris

  Betty Cooper
• 
  Jason Mantzoukas

  Jughead Jones
• 
  Clare Grant

  Sabrina Spellman
• 
  Tom Root

  (voice)
• 
  Betty Gilpin

  Veronica Lodge

• 
  Cree Summer

  Valerie Brown
• 
  Matthew Senreich

  Riverdale Pride Parade Announcer