• 
  Roy William Neill

  regizor

• 
  Scott Darling

  scenarist
• 
  Arthur Conan Doyle

  scenarist
• 
  Edward T. Lowe Jr.

  scenarist

• 
  Basil Rathbone

  Sherlock Holmes
• 
  Nigel Bruce

  Doctor John H. Watson
• 
  Lionel Atwill

  Profesorul James Moriarty
• 
  Mary Gordon

  Mrs. Hudson

• 
  Holmes Herbert

  Sir. Reginald
• 
  Dennis Hoey

  Lestrade
• 
  William Post Jr.

  Dr. Franz Tobel
• 
  Kaaren Verne

  Charlotte Eberli
• 
  Rudolph Anders
• 
  Ted Billings
• 
  Veda Ann Borg

• 
  Paul Bryar
• 
  John Burton
• 
  Harry Cording
• 
  James Craven
• 
  Harold De Becker
• 
  Jack Deery
• 
  Leslie Denison
• 
  George Eldredge
• 
  Paul Fix
• 
  Leyland Hodgson
• 
  Colin Kenny
• 
  Guy Kingsford
• 
  George Burr Macannan
• 
  Michael Mark
• 
  Henry Victor
• 
  Harry Woods

• 
  Howard Benedict

  producător
• 
  Lester White

  imagine
• 
  Vera West

  costume
• 
  Otto Ludwig

  montaj
• 
  Frank Skinner

  coloană sonoră
• 
  Russell A. Gausman

  decoruri