• 
  Jerry London

  regizor

• 
  Richard Chamberlain

  John Blackthorne / Anjin-san
• 
  Toshiro Mifune

  Toranaga
• 
  John Rhys-Davies

  Vasco Rodrigues
• 
  George Innes

  Vinck (unknown episodes)
• 
  Seiji Miyaguchi

  Muraji (unknown episodes)
• 
  Miiko Taka

  Kiri (unknown episodes)
• 
  Damien Thomas

  Father Alvito (unknown episodes)

• 
  Orson Welles

  Narrator (original version) (unknown episodes)
• 
  Shiro Mifune

  Lord Yoshi Toranaga (unknown episodes)
• 
  Alan Badel

  Father Dell'Aqua (unknown episodes)
• 
  Masashi Ebara

  Suga (unknown episodes)
• 
  Nobuo Kaneko

  Ishido (unknown episodes)
• 
  Shin Takuma

  Naga (unknown episodes)
• 
  Hyoei Enoki

  Jirobei (unknown episodes)

• 
  Yosuke Natsuki

  Zataki (unknown episodes)
• 
  Yoko Shimada

  Lady Toda Buntaro - Mariko (unknown episodes)
• 
  Frankie Sakai

  Yabu (unknown episodes)
• 
  Michael Hordern

  Friar Domingo (unknown episodes)
• 
  William Morgan Sheppard

  Specz (unknown episodes)
• 
  John J. Carney

  Gingel (unknown episodes)