• 
  Tony Goldwyn

  regizor

• 
  Hugh Jackman

  Eddie Alden
• 
  Ashley Judd

  Jane Goodale
• 
  Greg Kinnear

  Ray Brown
• 
  Marisa Tomei

  Liz
• 
  Ellen Barkin

  Diane Roberts
• 
  Laura Regan

  Evelyn
• 
  Joe Mosso

  Technician

• 
  Tony Goldwyn

  Narrator on TV
• 
  Mireille Enos

  Yoga Instructor #1
• 
  Catherine Dent

  Alice, Jane's Sister
• 
  Krysten Ritter

  Model
• 
  Colleen Camp

  Realtor
• 
  A.J. Ekoku

  Jane's Assistant
• 
  Shuler Hensley

  Hick Farmer

• 
  Murielle Arden

  Isabel
• 
  Veronica Webb

  Veronica Webb
• 
  Donna Hanover

  Mary Lou Corkle
• 
  Keith Reddin

  Male Scientist
• 
  Naomi Judd

  Makeup Artist
• 
  Matthew Coyle

  Staff Member
• 
  Peter Friedman

  Stephen, Alice's Husband
• 
  Derick Karlton Grant

  Flower Delivery Man
• 
  Nicole Leach

  Nia, Young Female Intern (as Nicole Leach)
• 
  Sue Jin Song

  Female Scientist
• 
  Pon Yang

  Chinese Vendor

• 
  Lynda Obst

  producător
• 
  Rolfe Kent

  coloană sonoră