• 
  Janeane Garofalo

  Herself
• 
  Ant

  Himself
• 
  Betty Dodson

  Herself
• 
  Ducky DooLittle

  Herself (as Dr. Ducky DooLittle)
• 
  Joani Blank

  Herself
• 
  Joycelyn Elders

  Herself
• 
  Patti Britton

  Herself (as Dr. Patti Britton)
• 
  Dennis Dortch

  Himself

• 
  M.J. Ecker

  Himself
• 
  Muhammad Ali

  Himself
• 
  Kelly Dennis

  Herself (as Professor Kelly Dennis)
• 
  Drew Fin-Kelson

  Himself
• 
  Martha Cornog

  Herself
• 
  Denise Acosta

  Herself

• 
  Larry Flynt

  Himself

• 
  Chris Gore

  Himself
• 
  Nina Hartley

  Herself