• 
  Marc Webb

  regizor

• 
  Steve Ditko

  scenarist
• 
  Stan Lee

  scenarist
• 
  Roberto Orci

  scenarist
• 
  Jeff Pinkner

  scenarist
• 
  James Vanderbilt

  scenarist
• 
  Alex Kurtzman

  scenarist

• 
  Jamie Foxx

  Electro / Max Dillon

• 
  Emma Stone

  Gwen Stacy
• 
  Dane DeHaan

  Harry Osborn / Green Goblin
• 
  Andrew Garfield

  Peter Parker / Omul-Păianjen
• 
  Tanner Flood
• 
  Stefano Villabona
• 
  Stefanie Bari

  Mallory
• 
  Stan Lee

• 
  Sarah Gadon

  Kari
• 
  Sally Field

  mătuşa May
• 
  Paul Giamatti

  Aleksei Sytsevich
• 
  Marton Csokas

  dr. Kafka
• 
  Martin Sheen

  unchiul Ben
• 
  Mark Doherty
• 
  Louis Cancelmi
• 
  Kari Coleman

  Helen Stacy
• 
  Jim Gunter

  Mike Stacy
• 
  Jenalyn Villegas
• 
  Frank Deal

  agentul Berkley
• 
  Felicity Jones

  Felicia
• 
  Embeth Davidtz

  Mary Parker
• 
  Denis Leary

  căpitanul Stacy
• 
  Dario Barosso
• 
  Colm Feore

  Donald Menken
• 
  Chris Zylka

  Flash Thompson
• 
  Chris Cooper

  Norman Osborn
• 
  Campbell Scott

  Richard Parker
• 
  B.J. Novak

  Alistair Smythe
• 
  Anslem Richardson
• 
  Alanna Blair
• 
  Max Charles

  Young Peter Parker

• 
  Roberto Orci

  producător
• 
  Matthew Tolmach

  producător
• 
  Beatriz Sequeira

  producător
• 
  Avi Arad

  producător
• 
  Alex Kurtzman

  producător
• 
  Daniel Mindel

  imagine
• 
  Deborah Lynn Scott

  costume
• 
  Pietro Scalia

  montaj
• 
  Elliot Graham

  montaj
• 
  Pharrell Williams

  coloană sonoră
• 
  Hans Zimmer

  coloană sonoră
• 
  Mark Friedberg

  design de producţie
• 
  Lucian Boicu

  efecte vizuale