• 
  Aidan Quinn

  Daniel Webster
• 
  Susanna Thompson

  Judith Webster
• 
  Christian Campbell

  Peter Webster
• 
  Phyllis Diller

  Jean (1 episode, 2006)
• 
  James Rebhorn

  Bertram Webster (7 episodes, 2006)
• 
  Dan Hedaya

  Father Frank (3 episodes, 2006)
• 
  Kathleen Chalfant

  Catherine Webster (1 episode, 2006)
• 
  David Harbour

  Kevin Warwick (1 episode, 2006)

• 
  Ellen Burstyn

  Bishop Beatrice Congreve (8 episodes, 2006)
• 
  Dylan Baker

  Roger Paxton (8 episodes, 2006)
• 
  Kat Foster

  Michelle Hedley (1 episode, 2006)
• 
  Al Whiting

  Police officer (7 episodes, 2006)
• 
  Gaius Charles

  Carver (1 episode)
• 
  Edward M. Kelahan

  Church Parishner  (5 episodes, 2006)
• 
  Gillian Jacobs

  Adele Congreve  (3 episodes, 2006)

• 
  Audra Blaser

  Vanessa Warwick (2 episodes, 2006)
• 
  David Rasche

  Donald Warwick (1 episode, 2006)
• 
  Enver Gjokaj

  David (1 episode, 2006)
• 
  Christopher Evan Welch

  Scott Clarkson (1 episode, 2006)
• 
  John Pankow

  Charlie (1 episode)
• 
  D.W. Moffett

  Worth Webster (1 episode, 2006)
• 
  Laila Robins

  Nora Paxton (3 episodes, 2006)
• 
  Alison Pill

  Grace Webster (8 episodes, 2006)
• 
  Marian Seldes

  Grandma Helen (1 episode, 2006)
• 
  Danny Mastrogiorgio

  Michael Vaporelli (2 episodes, 2006)
• 
  Halley Wegryn Gross

  Wanda (8 episodes, 2006)
• 
  Robert Clohessy

  Billy (2 episodes, 2006)
• 
  Marin Hinkle

  Nancy (1 episode, 2006)
• 
  Fredric Lehne

  Police Officer (1 episode, 2006)
• 
  Garret Dillahunt

  Jesus Christ (8 episodes, 2006)
• 
  Marcus Collins

  Server #1 (1 episode, 2006)
• 
  Alana De La Garza

  Jessie Gilmore (3 episodes, 2006)
• 
  Cheryl White

  Victoria Conlin (8 episodes, 2006)
• 
  Kelly Hu

   Kristine Ho (2 episodes, 2006)
• 
  Marco Barricelli

  Tony Vaporelli
• 
  Fran Bennett

  Rainy
• 
  Barbara Marineau

   Gloria (2 episodes, 2006)
• 
  Jonah Meyerson

  Yoda
• 
  Alice Playten

   Francesca (2 episodes, 2006)
• 
  Scott William Winters

  Jeffrey McMullen
• 
  Ivan Shaw

  Adam Webster
• 
  Leven Rambin

  Caroline Paxton
• 
  John Driscoll

  David Congreve
• 
  Kaija Matiss

   Becky (2 episodes, 2006)