• 
  Bryan Singer

  regizor
• 
  Stephen Surjik

  regizor

• 
  Matt Nix

  scenarist

• 
  Amy Acker

  Kate Stewart
• 
  Luis Albert Acevedo Jr.
• 
  Coby Bell

  Jace Turner
• 
  Stephen Moyer

  Reed
• 
  Jamie Chung

  Clarice Fong / Blink

• 
  Blair Redford

  Sam
• 
  Natalie Alyn Lind

  Lauren Strucker
• 
  Emma Dumont

  Lorna Dane
• 
  Percy Hynes White

  Andy
• 
  Sean Teale

  Marcos Diaz
• 
  Craig Cole
• 
  Stan Lee

• 
  Jeff Daniel Phillips
• 
  Sam Situmorang
• 
  Matthew Tompkins
• 
  Elena Satine

  Dreamer
• 
  Steffan Argus

   Jack - Lauren Strucker's Boyfriend (1 episode)
• 
  Bradley K. Jones

   Student (1 episode)
• 
  Gurie Sheffield

   Chaperone (1 episode)
• 
  Dale Godboldo

   Ted Baird (1 episode, 2017)
• 
  Billy Blair

   Trucker Driver (1 episode, 2017)
• 
  Jason Bremer

   Sentinel Service Man (1 episode, 2017)
• 
  Colin Beaton

   High School Student (1 episode, 2017)
• 
  Jessica Lia

   High School Student (1 episode, 2017)
• 
  Alex Nicole McConnell

   High School Student at dance (1 episode, 2017)
• 
  Hannah Mathes

   High School Student (1 episode, 2017)
• 
  Paul Caraway

   Sentinel Services Tech #1 (1 episode, 2017)
• 
  Abraham Mayne

   Scotty (1 episode, 2017)
• 
  Garret Dillahunt

   Dr. Roderick Campbell (4 episodes, 2017)
• 
  Hayley Lovitt

  Sage
• 
  James Sterling

  Mutant
• 
  Jermaine Rivers

  Shatter
• 
  Joe Nemmers

  9 episodes, 2017
• 
  Skyler Samuels

  Esme
• 
  Grace Gealey

  Reeva Payge
• 
  Tom O'Keefe

  Officer Wilson

• 
  Matt Nix

  producător
• 
  Bryan Singer

  producător
• 
  Neal Ahern Jr.

  producător
• 
  Jim Chory

  producător
• 
  Simon Kinberg

  producător
• 
  Jeph Loeb

  producător
• 
  Lauren Shuler Donner

  producător
• 
  Craig Siebels

  producător