• 
  Kathryn Shasha

   Shelby (14 episodes, 2016-2017)
• 
  Karen Ann Martino

   Meredith (14 episodes, 2016-2017)
• 
  Judith Maloney

   Ruth (8 episodes, 2017)
• 
  Tanja Melendez Lynch

   Helen (14 episodes, 2016-2017)
• 
  David Afflick

   Greg (14 episodes, 2016-2017)
• 
  Alexa Hartman

   The Girl (14 episodes, 2016-2017)
• 
  Jonathan Sartell

   Colton (14 episodes, 2016-2017)
• 
  Marty Smith

   The Woman in Black (14 episodes, 2016-2017)

• 
  Pamela Jayne Morgan

   Dr. Roberta Carson (7 episodes, 2016-2017)
• 
  Paul Taft

  Michael
• 
  Avery Hatch

  Lizzie
• 
  Rosemary Pacheco

  Miranda
• 
  Haley Pine

  Young Ruth
• 
  Damien Chinappi

  Ryan
• 
  Bella Moore

  Young Meredith

• 
  Herbert A. Fuchs

  George
• 
  Jennifer Gjulameti

  Laura
• 
  Lin Hultgren

  Nurse Janet
• 
  Luke Ryan

  Young Colton