• 
  Danny Leiner

  regizor

• 
  Sam Catlin

  scenarist

• 
  Olympia Dukakis

  Judy Hillerman
• 
  Jim Gaffigan

  Sandie
• 
  Judy Greer

  Allison Burbage
• 
  Maggie Gyllenhaal

  Emme Keeler
• 
  Edie Falco

  Safarah Polsky
• 
  Ari Graynor

  Lisa Krindel

• 
  Will Arnett

  Danny Keeler
• 
  Sam Catlin

  Councilman Blenick (segment "Judy's Story")
• 
  Marilyn Chris

  Phyllis (segment "Judy's Story")
• 
  Nancy McDoniel

  Agnes Whitehead (segment "Emme's Story")
• 
  Rosemarie DeWitt

  Debbie (segment "David and Allison's Story")
• 
  Anita Gillette

  Lainie (segment "Judy's Story")
• 
  Stephen Colbert

  Principal Peersall (segment "David and Allison's Story")

• 
  Tony Shalhoub

  Dr. Trabulous (segment "Sandie's Story")
• 
  Sharat Saxena

  Satish (segment "Avi and Satish's Story")
• 
  Tonye Patano

  Shirley (Meter Maid) (segment "Avi and Satish's Story")
• 
  Bernie McInerney

  Duff Krindel (segment "Emme's Story")
• 
  Seth Gilliam

  Clayton (segment "Emme's Story")
• 
  Tom McCarthy

  Davie Burbage (segment "David and Allison's Story")
• 
  Jim Parsons

  Justin (segment "Emme's Story")
• 
  Eliyas Qureshi

  Head Security Guard (segment "Avi and Satish's Story")
• 
  Alexis Dziena

  Angie
• 
  Meredith Ostrom

  Anita
• 
  Dawn Ressy

  Train Passenger