• 
  Fred Zinnemann

  regizor

• 
  Robert Anderson

  scenarist

• 
  Audrey Hepburn

  sora Luke
• 
  Peter Finch

  Dr Fortunati
• 
  Dean Jagger

  Dr. Van Der Mal
• 
  Barbara O'Neil

  Mother Didyma (War-time Hospital)
• 
  Gordon Heath

  Unnamed African native
• 
  Errol John

  Illunga (African convert)

• 
  Edith Evans

  Rev. Mother Emmanuel (Belgium)
• 
  Dorothy Alison

  Sister Aurelie (martyred nurse, Africa)
• 
  Penelope Horner

  Jeanette Milonet
• 
  Lionel Jeffries

  Dr. Goovaerts (School of Tropical Medicine)
• 
  Orlando Martins

  Kalulu (African servant)
• 
  Ave Ninchi

  Sister Bernard
• 
  Giovanna Galletti

• 
  Peggy Ashcroft

  Mother Mathilde (Africa)
• 
  Niall MacGinnis

  Father Vermeuhlen (Leprosarium)
• 
  Frank Singuineau

  Murderer of Sister Aurelie
• 
  Jeanette Sterke

  Louise (sister of Gabrielle)
• 
  Ruth White

  Mother Marcella (School of Medicine)
• 
  Rosalie Crutchley

  Sister Eleanor
• 
  Patricia Collinge

  Sister William (convent teacher)
• 
  Colleen Dewhurst

  Archangel Gabriel (Sanatorium)
• 
  Marc Evans

  Rev. Mother Emmanuel (Belgium)
• 
  Beatrice Straight

  Mother Christophe (Sanatorium)
• 
  Mildred Dunnock

  Sister Margharita (Mistress of Postulants)
• 
  Patricia Bosworth

  Simone (postulant who changed her mind)
• 
  Stephen Murray

  Chaplain (Father Andre)
• 
  Margaret Phillips

  Sister Pauline (medical student)