• 
  Stephen Frears

  regizor

• 
  John Hodge

  scenarist

• 
  Ben Foster

  Lance Armstrong
• 
  Lee Pace

  Bill Stapleton
• 
  Jesse Plemons
• 
  Chris O'Dowd

  David Walsh
• 
  Dustin Hoffman

  Bob Hamman
• 
  Laura Donnelly

  Emma O'Reilly

• 
  Lasco Atkins

  Journalist
• 
  Guillaume Canet

  Medecin Michele Ferrari
• 
  Elaine Cassidy

  Betsy Andreu
• 
  J.D. Evermore

  Lead Tailwind Exec
• 
  Chris Larkin

  John W
• 
  Mark Little

  (rumored)
• 
  Daniel Stewart

  Times Lawyer

• 
  Todd Terry

  Tailwind Exec
• 
  John Schwab

  Floyd's Attorney
• 
  Edward Hogg

  Frankie Andreu
• 
  Chiké Okonkwo

  Young Doctor
• 
  Sam Hoare

  Stephen Swart
• 
  Kari Kleiv

  Armstrong's PA
• 
  Christy Meyer

  US Sports Journalist
• 
  Ancuta Breaban

  Sales Person
• 
  Barrie Martin

  Diner
• 
  Claire Greasley

  Press camera woman
• 
  Jorge Leon Martinez

  Armstrong Best Man
• 
  Emilio Aniba

  Restaurant guest
• 
  Denis Ménochet

  Johan Bruyneel