• 
  Keanu Reeves

  Jesse Walker (1 episode, 1989)
• 
  Steve Martin

  Rusty DeClure (1 episode, 1987)
• 
  Bill Pullman

  Sheldon Moss
• 
  Isabella Rossellini

  Mae / Ilenia
• 
  Julie Condra

  Kim Tillman
• 
  Matthew Perry

  Craig
• 
  Tim Curry

  Ian Miles (1 episode, 1989)
• 
  Betty Thomas

  Miss Belts, Gym Teacher (1 episode, 1989)

• 
  Kelsey Grammer

  Mr. Brenna (1 episode, 1990)
• 
  Martin Short

  Doc the Elvis Presley freak  (2 episodes, 1989-1990)
• 
  Tracey Ullman

  Various Characters  (49 episodes, 1987-1990)
• 
  Nancy Cartwright

  Bart Simpson (28 episodes, 1987-1989)
• 
  Mel Brooks

  Buzz Schlanger (1 episode, 1990)
• 
  Cesar Romero

  Roland Diego (1 episode, 1988)
• 
  Fran Drescher

  Sales Assistant (1 episode, 1989)

• 
  Joey Miyashima

  Marty Jr. (1 episode, 1988)
• 
  Jane Carr

  Helen Havershim (1 episode, 1987)
• 
  William Hickey

  Claude the elderly millionaire (1 episode, 1988)
• 
  John Ashton

  Jimmy, neighborly doorman (1 episode, 1990)
• 
  Anne De Salvo

  Psychiatric Patient  (2 episodes, 1989)
• 
  Harvey Miller

  Fuzzy Bear  (2 episodes, 1987-1988)
• 
  Mike Starr

  Rude Dinner Patron (1 episode, 1988)
• 
  Julie Payne

  Dr. N!Godatu  (6 episodes, 1987)
• 
  Andrea Martin

  Therapy Paitent (1 episode, 1989)
• 
  Anna Levine

  Various Characters (8 episodes, 1988-1989)
• 
  Juliet Sorcey

  Missy (1 episode, 1989)
• 
  Michael Tucker

  Jo-Jo's Father (1 episode, 1989)
• 
  Judith Barsi

  Karen (2 episodes, 1987-1988)
• 
  Yeardley Smith

  Lisa Simpson (28 episodes, 1987-1989)
• 
  Marilu Henner

  Pregnant woman overdue #3 (1 episode, 1989)
• 
  Harold Sylvester

  David Black  (2 episodes, 1988-1989)
• 
  Brent David Fraser

  Jimmy (1 episode, 1990)
• 
  George Coe

  Reverend Graylin (1 episode, 1989)
• 
  Kellie Martin

  Kari, Slumber Party Girl (1 episode, 1988)
• 
  Doris Grau

  Carla, Office Worker  (3 episodes, 1988-1989)
• 
  Jim Piddock

  Derrick (1 episode, 1987)
• 
  Miriam Flynn

  Jill (1 episode, 1988)
• 
  Joseph Malone

  Various Characters  (40 episodes, 1987-1990)
• 
  Cheech Marin

  Azai, Convenience Store Owner (1 episode, 1987)
• 
  Sam McMurray

  Various  (43 episodes, 1987-1990)
• 
  Ken Foree

  Prison Warden (1 episode, 1988)
• 
  Robert Costanzo

  Big Tony Manetti (2 episodes, 1989-1990)
• 
  Dan Castellaneta

  Homer Simpson  (49 episodes, 1987-1990)
• 
  Adam Carl

  Martin (1 episode, 1987)
• 
  Nancy Miller

  Bart Simpson (28 episodes, 1987-1989)
• 
  Jacob Vargas

  Taco Place Manager (1 episode, 1987)