• 
  Jason Dudek

  regizor

• 
  Danny Glover

  dr. Locke
• 
  Taylor Handley

  Dean
• 
  Vinnie Jones

  Renner
• 
  Alan Gray

  DNA Tech
• 
  Ary Katz

  PFC Thornhill
• 
  Beverley Mitchell

  Isabelle
• 
  C.S. Lee

  Harvest Scientist

• 
  Casey Adams

  Scientist #4
• 
  Chad Todhunter

  Subject 003
• 
  Elizabeth Ann Koshak

  Airport Passenger / Lab Technician
• 
  Fiona Hale

  Sara
• 
  Jude Ciccolella

  Pharmaceutical CEO
• 
  Leebo Freeman

  Travis
• 
  Margo Harshman

  Mandy

• 
  Mo Gallini

  Sanchez
• 
  Rene Napoli

  DNA Supervisor
• 
  Ryan Pinkston

  Ricky
• 
  Shannon Kingston

  Locke's Assistant
• 
  Tiffany Hines

  Rhonda
• 
  Timothy Davis-Reed

  Scientist #3
• 
  Wiley M. Pickett

  Thompson

• 
  Greg Strasburg

  producător
• 
  Mark L. Lester

  producător executiv