• 
  Cliff Curtis

  Reuben 'Rabbit' Palchuk
• 
  Aimee Garcia

  Marisa Benez
• 
  Cynthia Lea Clark

  Nurse Slaughter
• 
  Steven Anthony Jones

  Captain Basra
• 
  Kevin Rankin

  Tyler Briggs
• 
  Jamey Sheridan

  Dr. Joseph Saviano
• 
  Derek Luke

  Cameron Boone
• 
  Ryan Michelle Bathe

  Sela Boone

• 
  Gina Beretta

  Nurse Gina
• 
  James D. Weston II

   Police Officer (18 episodes, 2009-2010)
• 
  Anastasia Griffith

  Nancy Carnahan
• 
  Taylor Kinney

  Glenn Morrison
• 
  Scottie Thompson

  Diana Van Dine
• 
  Karl Antony

  ER Nurse
• 
  Ruby Lopez

  Intern Dupuis

• 
  Christopher Greene

  Dr. Ludden
• 
  Carl Marino

  Karl Sly
• 
  Jeffrey T Ferguson

  EMT
• 
  Alice Kung

  Dr. Beale
• 
  Adrian Bustamante

  EMT
• 
  Deanna Marks

  Nurse Weisman
• 
  Jaclyn Winters

   Nurse (13 episodes, 2009-2010)
• 
  Steve Wharton

  EMT