• 
  Maya Stojan

  Tory Ellis
• 
  James Madio

  Eddie Maslon
• 
  Raphael Sbarge

  Dr. Darrell Meeks
• 
  Albie Selznick

  Dr. Paul Devlin
• 
  Aaron Hill

  Kurt Wilson
• 
  Matthew Holmes

  Chase Diggins
• 
  Arye Gross

  M.E. Sidney Perlmutter
• 
  Jon Huertas

  Javier Esposito

• 
  Tamala Jones

  Lanie Parish (credit only)
• 
  Seamus Dever

  Kevin Ryan
• 
  Nathan Fillion

  Richard Castle
• 
  Penny Johnson Jerald

  Captain Victoria Gates (credit only)
• 
  Molly C. Quinn

  Alexis Castle
• 
  Susan Sullivan

  Martha Rodgers
• 
  Stana Katic

  Kate Beckett